Recent highlights from the literature using interaction and pathway analyses
Researchers use an Enrichment Map to identify signaling pathways buried in gene expression data that enable regulatory T cells to prevent runaway activation of the immune system.
Cause and Effect
Winners of the DREAM 8 challenge to infer causality in a signaling network rely on pathways extracted from Pathway Commons
Pathway Commons data links known human cancer driver genes to kinases whose function is required to sustain tumor cell viability
Geneticists use Pathway Commons data to link gene implicated in leukemia to well-studied oxidative-stress pathways that maintain stem-cell renewal