KitReceptor (Pathway) from Homo sapiens
| Data Source: |
The Cancer Cell Map at Memorial Sloan-Kettering Cancer Center (http://cancer.cellmap.org) |
| Availability: |
Freely available from The Cancer Cell Map (created by Memorial Sloan-Kettering Cancer Center and the Institute of Bioinformatics) under the Creative Commons license (http://creativecommons.org/licenses/by/2.5/) |
| Comment: |
Tyrosine kinase is a transmembrane receptor that is expressed in a variety of different tissues and mediates pleiotropic biological effects through its ligand stem cell factor (SCF). Different kinases (like PI3K, PRKCB, Tec, Lyn) and adapter molecules (DOK1, SOCS1, SOCS6) are involved in Kit pathway. KIT pathway regulates gene expression of various types of proteins like transcription factors (MYB, MYC), ligands and receptors (TNF, Interleukins), adapter molecules (SOCS1, SOCS6). Many of them are involved in the KIT pathway itself.KIT pathway controls various cell processes like Cell Proliferation, Apoptosis, Chemotaxis. |
| View Expression Data on this Pathway |
Contains the Following Molecules (Showing 1 - 20 of 65) [display all]Contains the Following Interactions / Pathways (Showing 1 - 20 of 133) [display all]
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